Botulinum toxin treatment to eliminate wrinkles in Bari
Cardone Associated Medical Practice in Bari provides aesthetic treatments using Botulinum Toxin Type A, a protein produced by Clostridium Botulinum.
It is a polypeptide consisting of a light and a heavy chain linked by a single disulphide bridge. There are 8 known types of botulinum toxin (from A to G), structurally similar but serologically different.
The toxin acts by blocking neuromuscular conduction: the inhibition of acetylcholine release causes a flaccid muscle paralysis, and its function recovers as new neuromuscular junctions develop (usually after about 12 weeks).
Effects of Botulinum Toxin
Already on the market for several years with indications for the treatment of a wide range of neuromuscular disorders [Botulinum Toxin Type A (Botox, Dysport) and Type B (Neurobloc)], botulinum toxin is now available as a specific formulation for cosmetic use. The chance discovery of wrinkle reduction in areas adjacent to the injection has led to investigating its potential applications even in a non-medical context.
When injected into the corrugator and procerus muscles, the toxin antagonizes their contraction: the muscle elongates, and the overlying skin flattens, reducing wrinkles, folds, and creases. The effect is typically visible within 3 days of administration, reaching its maximum after 2 weeks, and disappears upon muscle function recovery, typically within 3-6 months.
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